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Fat Cells and Insulin

Fat production in adipocytes is strongly stimulated by insulin. By controlling the activity of the pyruvate dehydrogenase and the acetyl-coA  enzymes, insulin promotes unsaturated fatty acid synthesis.  It also promotes glucose uptake  and induces SREFB1, which activates the transcription of genes that stimulate lipogenesis. Clinical studies have repeatedly shown that even though insulin resistance is …

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Sleep

Sleep is one of the most under-appreciated tools in the fight against obesity.  Adequate and quality daily sleep helps regulate hormones of food intake and stress.  It is important to ask about getting a sleep study if you think that you are not getting adequate, quality sleep

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What are fat cells?

Fat cells do not just carry lipid or “fat” the also have mitochondria which make them very active producing thousands of by products such as hormones, inflammatory markers, etc…

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Ozempic Weight Loss

Yes ozempic does help people lose weight.   In fact, all GLP-1 Agonists help people lose weight.  The problem with using GLP1 agonists in weight loss is that a lot of people do a severe calorie restriction.  This needs to be supervised by a healthcare provider or physician.   A severe calorie restriction is not needed to …

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